Orthoses
Bracing for adolescent idiopathic scoliosis: evidence and guidance
Does a brace really help avoid surgery? A summary of the BrAIST trial, the Cochrane reviews, SOSORT guidance and management by Cobb angle.
Adolescent idiopathic scoliosis (AIS) affects about 2–3% of children at puberty. For children with a large enough curve who are still growing, bracing is the only non-surgical treatment proven in a multicentre randomised trial to reduce the rate of surgery.
This article summarises the latest studies and international guidance in plain language, with practical advice for parents. It is for information and does not replace advice from a specialist.
1. What is adolescent idiopathic scoliosis?
Adolescent idiopathic scoliosis (AIS) is a three-dimensional deformity of the spine that begins at puberty without a known cause. It is diagnosed when the Cobb angle on X-ray is 10° or more, usually with vertebral rotation and an unbalanced trunk.
Epidemiology. About 80% of scoliosis cases are idiopathic, and AIS is the most common form at 2–3%. A 2026 global meta-analysis in Spine (data 1975–2025) found that clinically significant AIS, a Cobb angle of 20° or more, has a prevalence of 0.28%. It is more common in girls than in boys.
Psychological burden. A 2026 systematic review in Health Expectations pooled 19 qualitative studies from 10 countries (323 participants). Stigma, prejudice and lack of psychological support made the experience of children and carers heavier. A 2025 physiotherapy review noted that more than 30% of AIS patients under observation or in a brace had clinically significant psychological distress.
2. Without treatment, how will the curve progress?
About 4 in 10 children with AIS have curve progression if untreated. The meta-analysis of Di Felice et al. (2018) in the American Journal of Physical Medicine & Rehabilitation estimated progression at 42% in AIS and 49% in a mixed juvenile–adolescent group.
- The most dangerous phase is the pubertal growth peak. The risk of progression varies with stage of growth and is highest during rapid growth.
- Curve type affects risk. Single thoracic and double curves progress more than lumbar or thoracolumbar curves.
- The 50° threshold shapes adult life. After growth ends, a curve above 50° has a high risk of continuing to progress in adulthood.
- In the high-risk group, more than half reach the surgical threshold. In BrAIST's observation group (Cobb 20°–40°, Risser 0–2), only 48% of children reached the end of growth with a curve still below 50°.
- Lonstein and Carlson (JBJS Am 1984), in 727 children with an initial curve of 5°–29°: 23.2% progressed; skeletal maturity (Risser) and curve size were among the strongest predictors.
This is why intervention must happen while the child is still growing: it is the only period in which a brace can change the course of the disease.
What happens in adulthood without treatment? The 50-year follow-up of Weinstein et al. (JAMA 2003) of 117 untreated people with late-onset idiopathic scoliosis versus 62 controls: survival was similar to the general population (about 0.55 versus 0.57); 61% had chronic back pain versus 35% of controls, most of it only mild to moderate; 22% had shortness of breath in daily activities versus 15%, with a higher risk when the Cobb angle exceeded 80° with a thoracic apex. The authors concluded that untreated adults remain productive and functional. This puts the goal in proportion: treatment at puberty aims to stop the curve reaching a severe level, and decisions must be individualised for each child.
3. Diagnosis and assessment
Treatment decisions rest on three main parameters: curve size, skeletal maturity and rate of progression.
| Parameter | Meaning | Clinical note |
|---|---|---|
| Cobb angle (degrees) | Size of the curve on a standing X-ray | AIS is diagnosed at ≥ 10°; measurement error about ±5° |
| Risser sign (0–5) | Ossification of the iliac crest, reflecting remaining growth potential | Risser 0–3 = still growing, the SOSORT indication for bracing |
| Menstrual status (girls) | A marker of pubertal stage | No periods yet, or under 1 year after the first, is the criterion for still growing in many trials |
| Angle of trunk rotation (ATR) | Measured with a scoliometer as the child bends forward (Adams test) | For screening and follow-up; does not replace X-ray |
A note on error and X-rays. Because measurement error is about 5°, changes smaller than that should not be taken as real improvement or worsening. The authors of the 2026 network meta-analysis also stress that follow-up X-rays should not be repeated at less than 6-month intervals without a clinical indication, to limit cumulative radiation.
4. Evidence for the effectiveness of bracing in scoliosis
Bracing is the only non-surgical treatment for scoliosis proven in a multicentre randomised trial to reduce the rate of surgery.
4.1. The BrAIST trial (NEJM, 2013)
BrAIST was a multicentre trial in the US and Canada of 242 children with a Cobb angle of 20°–40°, Risser 0–2, aged 10 to under 15, who wore a rigid TLSO or were observed only. The outcome was whether the child reached skeletal maturity with a Cobb angle below 50°.
- 72% of children wearing a corrective brace had success, versus 48% in the observation group.
- The trial was stopped early because the benefit of bracing was already clear.
- The benefit was seen in both the randomised group and the as-treated group.
4.2. The dose–response relationship: hours worn decide the result
Temperature sensors inside the brace recorded the real hours worn. Hours worn were closely linked to the success rate (P < 0.001).
In the trial children were told to wear the brace at least 18 hours a day, but actual wear depended on the curve. The review of Karavidas (2019) also pooled studies showing that those wearing more than 90% of the prescribed hours had an 11% progression rate, versus 56% among the non-adherent.
4.3. The Cochrane reviews
- The 2015 Cochrane review of braces included 7 studies with 662 children of both sexes, assessing elastic, rigid and very rigid braces. All studies consistently showed that bracing prevents curve progression. Bracing did not change quality of life during treatment.
- An earlier version of this review found rigid braces more effective than soft elastic ones.
- The certainty of the evidence in the Cochrane reviews was rated low to very low, mainly because randomised trials are hard to design. BrAIST later added level I evidence.
- The history of the evidence should be stated plainly: before BrAIST, the review by Dolan and Weinstein (Spine 2007, 18 level III–IV studies) pooled a surgery rate of about 23% after bracing and 22% after observation, found no clear advantage of either and graded the recommendation D. Because the evidence was inconclusive, a randomised trial such as BrAIST was needed.
- A Japanese study (Kuroki et al., Scoliosis 2015) of 31 children using the Osaka Medical College brace under SRS criteria: success rate 67.7%, clearly higher in those adhering to more than 50% of the prescribed hours (88.2% versus 42.8%). A small sample, but the same direction as BrAIST: wearing it for enough hours works better.
4.4. Predictors of successful bracing
- In-brace correction: a 2019 best-evidence synthesis in the European Spine Journal showed that lack of initial in-brace correction is strongly linked to treatment failure. This is why design and manufacturing quality matter so much.
- Wear time is linked to success or failure at a moderate level of evidence.
- Skeletal maturity. Karol et al. found that Risser 0 children with an open triradiate cartilage have a higher failure risk; they suggest Risser 0 children should wear the brace at least 18 hours a day.
4.5. Improving adherence
- Sensor monitoring with counselling. In the study by Karol et al. (JBJS 2016), patients were counselled using sensor data. Children who did not need surgery wore the brace significantly more hours a day than those who did (p = 0.029).
- A 2022 meta-analysis in PLOS ONE showed that electronic monitoring increased mean wear time by 3.47 hours a day compared with no monitoring.
- Patient motivation. More than 90% of patients said their main motivation was to avoid surgery and stop the curve getting worse. Summer and school hours are the hardest times to comply; many have pain and skin irritation.
- Self-image. BrAIST data did not show a difference in self-image between low-wear and high-wear groups over 2 years of follow-up.
A worked example: in-brace correction and treatment effect (one sample case)
To show what “in-brace correction” means, we use a sample case from the clinic: a 15-year-old (born 2007) with a single C-shaped lumbar curve, apex L1, Cobb angle 38.65° (film of 2 August 2022). Treatment was with two individualised braces (day and night), periodic review at each stage and exercise. The patient adhered very well to the wearing schedule.
How to read it: in-brace correction is the Cobb angle measured on a film taken while wearing the brace, compared with the angle out of the brace. The difference between the two films is the corrective force the brace produces. A negative number means the curve is pushed past straight to the opposite side.
| Date of film | Condition | Cobb angle |
|---|---|---|
| 2 Aug 2022 | Before treatment, no brace | 38.65° |
| 24 Oct 2023 (after about 14 months) | Out of brace | 10° |
| 24 Oct 2023 | In the night brace | −2.6° (over-corrected to the opposite side) |
| 24 Oct 2023 | In the day brace | 0.2° |
| 28 Jun 2024 (latest review) | Out of brace | 2.2° (upper curve) and 1.6° (lower curve) |
| 28 Jun 2024 | In the day brace | 2.5° and −6.3° |
| 28 Jun 2024 | In the night brace | 2.0° and −7.0° |
Reading the numbers: out of the brace the curve fell from 38.65° to 10°, about 74%. On the film of 24 October 2023, compared with 10° out of the brace, the day brace brought the curve to about 0° and the night brace over-corrected it to a negative value. At the review of 28 June 2024 both braces were still “negative”, and the patient had completed the final stage of weaning off the day brace. At that review the software measured two angles (upper and lower curve), so each row has two numbers.
Why does in-brace correction matter? The best-evidence synthesis of van den Bogaart et al. (Eur Spine J 2019; 26 studies) concluded that there is strong evidence that a lack of initial in-brace correction is associated with treatment failure, and moderate evidence that wear time is associated with both failure and success; the authors call for research on a minimum correction threshold. The Boston-brace study of Emans et al. (Spine 1986; 295 patients, best in-brace correction about 50% on average) found that greater in-brace correction predicted better correction later. Katz et al. (JBJS Am 2010; 100 completers) recorded no progression in 82% of those wearing the brace more than 12 hours a day, versus 31% of those wearing it under 7 hours. The 2016 SOSORT guidelines also call for periodic X-rays to check the brace’s effect.
Note: this is an association, not proof of cause and effect; one child’s result also depends on age, skeletal maturity, curve pattern and adherence (this case adhered very well), so it does not represent every child. In-brace correction should also not be chased at any cost: a good brace balances corrective force, comfort and the ability to wear it for enough hours.
5. Types of brace for scoliosis
Most corrective scoliosis braces today are thoraco-lumbo-sacral orthoses (TLSO). In 2022 SOSORT, together with SRS, ISPO and POSNA, developed a new brace classification system, endorsed by ESPRM.
| Type of brace | Wear time | Main evidence |
|---|---|---|
| Rigid full-time brace (TLSO, e.g. Boston, Chêneau) | Prescribed 18–23 hours/day | BrAIST: 72% success, 90–93% when worn ≥ 12.9 hours/day |
| Hypercorrective night brace | 8 hours/night | CONTRAIS: success rate 76% |
| Soft elastic brace | As prescribed | Less effective than a rigid brace |
| Very rigid brace / casting | As prescribed by a specialist | SOSORT recommends for curves of 45°–60° to try to avoid surgery |
Night bracing: a new option with randomised evidence. The CONTRAIS trial was carried out in 6 public hospitals in Sweden from 2013 to 2018 with 135 children with moderate AIS. The night-brace-plus-physical-activity group had a 76% success rate. This was higher than the specific-exercise group (58%) and the physical-activity-only group (53%). A secondary analysis found in-brace correction of the main curve of 48% with the night brace and 51% with the full-time brace; the two had equivalent effectiveness.
How is the brace made? According to SOSORT, every stage from prescription and manufacture to checking, adjustment and follow-up must strictly follow brace-management standards for each individual brace. Effectiveness depends on the correction achieved when worn, so a skilled orthotic engineer is the key factor.
6. Schroth and scoliosis-specific exercises (PSSE)
Scoliosis-specific exercises give a small but real benefit, and work best combined with a brace, not replacing it.
PSSE (Physiotherapeutic Scoliosis-Specific Exercises), including the Schroth method, focus on three-dimensional self-correction, posture control, rotational breathing and neuromuscular retraining. A randomised trial in Turkey showed that the group doing three-dimensional Schroth exercises for 6 months had better Cobb angle results than the observation-only group.
| Study | Design | Main result |
|---|---|---|
| Romano et al., Cochrane 2024 | Review of 13 RCTs, 583 people, 9 countries | Therapeutic exercise and braces both struggle to improve self-image and quality of life |
| Bayesian network meta-analysis, 2025 | RCTs of exercise, searched to 08/2024 | Combined Schroth reduced the Cobb angle by a mean of 4.79°; PSSE by 3.11° compared with controls |
| Exercise review for moderate AIS, 2025 | 8 RCTs, Cobb angle 20°–45° | Exercise alone was equivalent to bracing at 6 months; exercise combined with another therapy had short-term benefit for Cobb angle, quality of life and respiratory function |
| CONTRAIS, JAMA Netw Open 2024 | RCT in Sweden, moderate AIS | Night brace 76% success, specific exercises 58%, physical activity only 53% |
| Yang et al., Front Pediatr 2026 | Network meta-analysis, 13 studies, 709 patients | Bracing and Schroth groups tended to control the Cobb angle best in the short term; evidence sparse and highly heterogeneous |
Reading the numbers correctly. A 3–5° reduction sits close to the measurement error of the Cobb angle (±5°). Exercise should therefore be seen as a supportive therapy for posture control and for giving the child an active role, rather than a stand-alone way of straightening the curve. Clinical guidelines recommend that physiotherapy complement the brace and not replace it for moderate curves. SOSORT also recommends specific spinal mobilisation exercises to prepare for bracing. The evidence for exercise has improved a lot: the first Cochrane review (2013) found only 2 studies with 154 people at very low certainty, whereas the 2024 update has 13 randomised trials.
7. International recommendations and management by Cobb angle with bracing
The international societies agree that a child who is still growing, with a curve of about 20°–25° or more and a risk of progression, should be braced.
SOSORT 2016 guidance (published 2018):
- Bracing is recommended for curves above 20° ± 5°, in children still growing (Risser 0–3), that have progressed or are at high risk of progression.
- Full-time wear, or not less than 18 hours a day in the initial phase.
- Periodic out-of-brace X-rays to check effectiveness; the hours out of the brace before the X-ray correspond to the daily weaning time.
- A very rigid brace or casting for curves of 45°–60° to try to avoid surgery.
- The guideline has 68 recommendations, of which 2 on bracing and 1 on PSSE reached recommendation grade I, evidence level II.
SRS criteria for bracing studies: age 10 or more, Risser 0–2, Cobb angle 25°–40°, premenarchal or under 1 year after the first period. This is also the group of patients who benefit most clearly from bracing in the trials.
Reference management by Cobb angle
| Cobb angle | Skeletal status | Management |
|---|---|---|
| Under 15° | Any stage | Regular monitoring |
| Under 20° | Skeletally mature | Regular monitoring |
| 15°–25° | Still growing | Schroth/PSSE exercises as first-line supportive therapy; close follow-up of progression |
| 20°–25° or more | Still growing (Risser 0–3), progressing | Brace combined with exercises |
| 25°–40° | Still growing | Bracing has the best evidence; success depends on adherence |
| 45°–60° | Still growing | Very rigid brace or casting to try to avoid surgery |
| 50° or more | Any stage | The usual threshold for considering surgery |
This is a reference framework. The treatment decision needs a specialist to individualise it by age, skeletal maturity, curve pattern, risk of progression and the family's wishes.
8. Practical advice for parents and patients
The most important thing parents can do is detect early and help their child wear the brace for enough hours.
- Watch for early signs. Uneven shoulders, one shoulder blade sticking out, an uneven waist, or a rib hump on one side when the child bends forward.
- See a specialist and have an X-ray to measure the Cobb angle and assess Risser and curve pattern.
- Intervene while the child is still growing. This is the period of highest risk of progression and also the only time a brace can change the course of the disease.
- Choose a brace made by the proper process. It must be measured and designed for the child's own body and curve, its in-brace correction checked, and adjusted as the child grows.
- Make sure enough hours are worn. Wearing 12.9 hours a day or more gives a 90–93% success rate, whereas under 6 hours a day is hardly different from not wearing it.
- Monitor wear time. If possible use a brace with a sensor; electronic monitoring raises wear by more than 3 hours a day on average.
- Combine with specific exercises under the guidance of a physiotherapist trained in Schroth/PSSE.
- Look after the skin and deal with discomfort. Pain and skin irritation are common reasons children stop wearing the brace; tell the orthotic engineer so it can be adjusted early.
- Support emotionally. Talk to your child about the goal of avoiding surgery, which is the main motivation of more than 90% of patients. Support from friends can also help adherence.
- Attend follow-up as scheduled by the doctor, usually not sooner than 6 months between two X-rays unless there is a special indication.
Some photos of custom braces at the clinic
A brace is made for each child's own body and curve, its in-brace correction checked and adjusted as the child grows.
If your child has signs of scoliosis or has been prescribed a brace, bring the X-rays for an in-person examination and consultation. Hotline +84 985 211 888.
References
- Weinstein SL, Dolan LA, Wright JG, Dobbs MB. Effects of bracing in adolescents with idiopathic scoliosis. N Engl J Med. 2013;369(16):1512–1521.
- Negrini S, Minozzi S, Bettany-Saltikov J, et al. Braces for idiopathic scoliosis in adolescents. Cochrane Database Syst Rev. 2015;(6):CD006850.
- Romano M, Minozzi S, Bettany-Saltikov J, et al. Therapeutic exercises for idiopathic scoliosis in adolescents. Cochrane Database Syst Rev. 2024;2:CD007837.
- Negrini S, Donzelli S, Aulisa AG, et al. 2016 SOSORT guidelines: orthopaedic and rehabilitation treatment of idiopathic scoliosis during growth. Scoliosis Spinal Disord. 2018;13:3.
- Yang S, Cai F, Xie R, et al. Adolescent idiopathic scoliosis non-surgical interventions: a systematic review and network meta-analysis of Cobb angle and SRS-22 outcomes. Front Pediatr. 2026;14:1908709.
- Po EYP, Yang M, Takemura N, et al. Global prevalence of adolescent idiopathic scoliosis between 1975 and 2025: a systematic review and meta-analysis. Spine. 2026.
- Kuru T, Yeldan İ, Dereli EE, et al. The efficacy of three-dimensional Schroth exercises in adolescent idiopathic scoliosis: a randomised controlled clinical trial. Clin Rehabil. 2016;30(2):181–190.
- Wang S, Zhao J, Hu X, et al. Psychosocial burden of adolescent idiopathic scoliosis: a systematic review and meta-synthesis of patient and caregiver perspectives. Health Expect. 2026.
- The effects of exercise on patients with moderate adolescent idiopathic scoliosis: a systematic review and meta-analysis. Orthop Rev. 2025. PMID: 40476023.
- Physiotherapy management of adolescent idiopathic scoliosis (Invited Topical Review). J Physiother. 2025.
- Di Felice F, Zaina F, Donzelli S, Negrini S. The natural history of idiopathic scoliosis during growth: a meta-analysis. Am J Phys Med Rehabil. 2018;97(5):346–356.
- Puberty changes the natural history of idiopathic scoliosis: three prediction models for future radiographic curve severity from 1563 consecutive patients. Eur Spine J. 2024.
- Prediction of future curve angle using prior radiographs in previously untreated idiopathic scoliosis: natural history from age 6 to after the end of growth (SOSORT 2022 award winner). Eur Spine J. 2023.
- Karol LA, Virostek D, Felton K, Jo C, Butler L. The effect of the Risser stage on bracing outcome in adolescent idiopathic scoliosis. J Bone Joint Surg Am. 2016;98(15):1253–1259.
- Hình ảnh minh họa / Illustrations: dungcuchinhhinh.vn (website của Lê Hoàn Prosthetics & Orthotics)
- Cheng JC, Castelein RM, Chu WC, et al. Adolescent idiopathic scoliosis. Nat Rev Dis Primers. 2015;1:15030. PMID 27188385.
- Weinstein SL, Dolan LA, Spratt KF, et al. Health and function of patients with untreated idiopathic scoliosis: a 50-year natural history study. JAMA. 2003;289(5):559–567. PMID 12578488.
- Lonstein JE, Carlson JM. The prediction of curve progression in untreated idiopathic scoliosis during growth. J Bone Joint Surg Am. 1984;66(7):1061–1071. PMID 6480635.
- Dolan LA, Weinstein SL. Surgical rates after observation and bracing for adolescent idiopathic scoliosis: an evidence-based review. Spine. 2007;32(19 Suppl):S91–S100. PMID 17728687.
- Karavidas N. Bracing in the treatment of adolescent idiopathic scoliosis: evidence to date. Adolesc Health Med Ther. 2019;10:153–172. PMID 31632169.
- Kuroki H, Inomata N, Hamanaka H, et al. Efficacy of the Osaka Medical College (OMC) brace in the treatment of adolescent idiopathic scoliosis following Scoliosis Research Society brace studies criteria. Scoliosis. 2015;10:12 (Japan). PMID 25932040.
- Kuroki H. Brace treatment for adolescent idiopathic scoliosis. J Clin Med. 2018;7(6):136 (Japan). PMID 29867010.
- van den Bogaart M, van Royen BJ, Haanstra TM, de Kleuver M, Faraj SSA. Predictive factors for brace treatment outcome in adolescent idiopathic scoliosis: a best-evidence synthesis. Eur Spine J. 2019;28(3):511–525. PMID 30607519.
- Emans JB, Kaelin A, Bancel P, Hall JE, Miller ME. The Boston bracing system for idiopathic scoliosis: follow-up results in 295 patients. Spine. 1986;11(8):792–801. PMID 3810295.
- Katz DE, Herring JA, Browne RH, Kelly DM, Birch JG. Brace wear control of curve progression in adolescent idiopathic scoliosis. J Bone Joint Surg Am. 2010;92(6):1343–1352. PMID 20516309.
- Almansour H, Pepke W, Bruckner T, Diebo BG, Akbar M. Three-dimensional analysis of initial brace correction in the setting of adolescent idiopathic scoliosis. J Clin Med. 2019;8(11):1804. PMID 31661811.
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